آلزایمر ممکن است مدت‌ها قبل از ظهور پلاک‌ها روی مغز اثر بگذارد

Alzheimer’s may leave a mark on the brain long before plaques appear

Brain changes associated with Alzheimer’s may begin at least seven years before amyloid plaques become detectable with current PET scans. Researchers uncovered the signal by tracking healthy older adults with repeated brain imaging over nearly 20 years. The discovery could help scientists identify Alzheimer’s earlier and suggests that important disease processes may start before visible plaque buildup.