پیش‌بینی محدودیت‌های عملکردی در سطح ژنوم با GPN-Star

Predicting genome-wide functional constraints with GPN-Star

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11005-5 GPN-Star, a genomic language model with a phylogeny-aware architecture for whole-genome alignment data, is shown to be a scalable and flexible tool for genetic variant effect prediction across species.